Diagnostic agreement between bronchoalveolar lavage and transbronchial lung biopsy in patients with suspected pulmonary diseases: A single-center study

Our findings underscore the critical role of BAL cytology in the diagnosis of pulmonary carcinoma and infectious processes while also revealing its limitations in detecting interstitial lung diseases. The TBLB procedure emerges as an indispensable technique for accurate histopathological evaluation in lung cancer diagnostics. The integration of BAL and TBLB not only enhances diagnostic yield but also provides a more comprehensive understanding of pulmonary pathologies. Notably, we found moderate agreement between BAL and TBLB in neoplastic cases and fair agreement in non-neoplastic conditions, suggesting a nuanced interplay between these methodologies that could inform clinical practice and improve patient outcomes. This study advocates a combined approach in diagnostic frameworks to optimize the management of patients with suspected pulmonary diseases, paving the way for more precise and effective diagnoses in the field of cytology.

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Publication Details

Journal
CytoJournal
Published
2025-04-09
DOI
https://doi.org/10.25259/cytojournal_205_2024
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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article
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article

Diagnostic agreement between bronchoalveolar lavage and transbronchial lung biopsy in patients with suspected pulmonary diseases: A single-center study

Nirush Lertprasertsuke, Chindanai Namwong, Phichayut Phinyo, Komson Wannasai et al.
CytoJournal
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Diagnostic agreement between bronchoalveolar lavage and transbronchial lung biopsy in patients with suspected pulmonary diseases: A single-center study

Nirush Lertprasertsuke, Chindanai Namwong, Phichayut Phinyo, Komson Wannasai, Sarawut Kongkarnka, Wiyada Dankai, Sayanan Chowsilpa, Tanapol Yaowarat, Phurinut Suwatwiriyapong, Pongsapat Vacharothone, Sansern Chankasemporn
article en

Abstract

Our findings underscore the critical role of BAL cytology in the diagnosis of pulmonary carcinoma and infectious processes while also revealing its limitations in detecting interstitial lung diseases. The TBLB procedure emerges as an indispensable technique for accurate histopathological evaluation in lung cancer diagnostics. The integration of BAL and TBLB not only enhances diagnostic yield but also provides a more comprehensive understanding of pulmonary pathologies. Notably, we found moderate agreement between BAL and TBLB in neoplastic cases and fair agreement in non-neoplastic conditions, suggesting a nuanced interplay between these methodologies that could inform clinical practice and improve patient outcomes. This study advocates a combined approach in diagnostic frameworks to optimize the management of patients with suspected pulmonary diseases, paving the way for more precise and effective diagnoses in the field of cytology.

CytoJournalVol. 22
Chiang Mai University (TH)
Openalex Percentile: Top 89%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Diagnostic agreement between bronchoalveolar lavage and transbronchial lung biopsy in patients with suspected pulmonary diseases: A single-center study — Nirush Lertprasertsuke, Chindanai Namwong, et al. · CytoJournal (2025) | TGRS Research Map | TGRS