Reproducible Effects of Sex and Acquisition Order on Multiple Global Signal Metrics: Implications for Functional Connectivity Studies of Phenotypic Individual Differences Using fMRI
Together, the findings suggest that FC relationships with affective measures may be inconsistent or modest, but that global phenomena related to state and individual differences can be robust and must be evaluated, particularly in studies of psychiatric disorders such as mood disorders or ADHD, which show sex differences.
Authors
- Richelle Stiffler (ORCID: https://orcid.org/0000-0001-7876-4586)
- Alexander Skeba
- Danella Hafeman (ORCID: https://orcid.org/0000-0001-8312-3513)
- Tyler M. Brady (ORCID: https://orcid.org/0009-0003-7434-7111)
- Lisa Bonar (ORCID: https://orcid.org/0000-0002-9826-2505)
- Genna Bebko
- Simona Graur (ORCID: https://orcid.org/0000-0003-0063-1657)
- Merage Ghane (ORCID: https://orcid.org/0000-0002-3396-4784)
- Henry W. Chase (ORCID: https://orcid.org/0000-0001-9780-095X)
- Michele A. Bertocci (ORCID: https://orcid.org/0000-0002-3857-1226)
- Mary L. Phillips (ORCID: https://orcid.org/0000-0003-4958-1291)
- Satish Iyengar
- Haris Aslam
Institutions
- University of Pittsburgh (US)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/brb3.70141
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Pittsburgh Foundation
- University of Pittsburgh
- National Institutes of Health
- Center for Research Computing, University of Pittsburgh
- National Institute of Mental Health