Causal associations between environmental factors and risk of IgA nephropathy and membranous nephropathy: a bidirectional Mendelian randomization and mediation analysis

This study provides novel evidence of causal relationships between 20 genetically predicted environmental factors and the risk of IgAN and MN. These findings may inform targeted prevention strategies and contribute to improved disease risk assessment.

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Publication Details

Journal
Renal Failure
Published
2025-04-09
DOI
https://doi.org/10.1080/0886022x.2025.2486620
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Causal associations between environmental factors and risk of IgA nephropathy and membranous nephropathy: a bidirectional Mendelian randomization and mediation analysis

Jun Wu, Chunmin Li, Wen Qian, Yanxia Zhang
1 links
Renal Failure
Renal Diseases and Glomerulopathies
article

Causal associations between environmental factors and risk of IgA nephropathy and membranous nephropathy: a bidirectional Mendelian randomization and mediation analysis

Jun Wu, Chunmin Li, Wen Qian, Yanxia Zhang
article en

Abstract

This study provides novel evidence of causal relationships between 20 genetically predicted environmental factors and the risk of IgAN and MN. These findings may inform targeted prevention strategies and contribute to improved disease risk assessment.

Renal FailureVol. 47(1)
Tongren Hospital (CN), Wuhan Third Hospital (CN)
Zero hunger
Openalex Percentile: Top 91%
Renal Diseases and Glomerulopathies
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