Layer-by-Layer Engineering of Black Seed Oil Based SNEDDSs (BSO-SNEDDSs): Optimizing Chemical Stability and Bioavailability in Ramipril Formulations
While liquid SNEDDSs exhibit promisingly greater oral bioavailability than crystalline drugs do, the performance of multilayer solid SNEDDSs necessitates further refinement. Nonetheless, this comprehensive investigation establishes a robust foundation for continued research on multifunctional bioactive oil-based SNEDDSs to enhance the bioavailability of drugs with limited water solubility.
Authors
- Ehab Mostafa Elzayat (ORCID: https://orcid.org/0000-0001-5177-4477)
- Abdelrahman Y. Sherif (ORCID: https://orcid.org/0000-0003-1842-6010)
- Ahmad Abdul-Wahhab Shahba (ORCID: https://orcid.org/0000-0003-4509-8219)
- Mohsin Kazi (ORCID: https://orcid.org/0000-0002-5611-0378)
- Shaukat Ali (ORCID: https://orcid.org/0000-0002-9979-3519)
Institutions
- King Saud University (SA)
- Brunswick (United States) (US)
- Ascendis Pharma (Denmark) (DK)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s510918
- Citations
- 2
- Primary Topic
- Enzyme Catalysis and Immobilization
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- King Abdulaziz City for Science and Technology
- National Plan for Science, Technology and Innovation