Subcortical Brain Regions Associated With Seizure Risk in Patients With IDH Mutated Diffuse Gliomas

The study provides new insights into the epileptogenic potential of diffuse gliomas in relation to their spatial distribution, highlighting the need to analyse both cortical and subcortical localisation of tumours. The observed differences in seizure risks across brain regions underscore the need for personalised post-surgery treatment strategies and further research to understand the pathophysiology of brain tumour-related epilepsy, BTRE.