Unveiling The Potency: Antibacterial activities of Four Plants’ Extracts against Isolated Bacteria from Burn wounds

Background: Antimicrobial resistance has emerged as a truly serious issue. Motivating the scientific community to explore natural compounds as alternative treatments for infections, with a focus on plant-derived antimicrobials. Objective: The extract of following plants (Pelargonium graveolens, Centaurea hyalolepis, Rosa damascena, Portulaca olereaca) was tested for antibacterial activity. Methods: The bacterial specimens were collected from the Burns unit of Al-Mouwasat university hospital, and isolated by biochemical tests and morphological properties. The herbal ethanolic extracts were prepared by Soxhlet apparatus, and MICs were performed by macrodilution method. Results: we detected five main bacterial strains (Staphylococcus aureus, Staphylococcus epidermis, Klebsiella pneumonia, Pseudomonas aeruginosa, and Escherichia coli) from the collected specimens. The results were variable: P. graveolens showed lowest MIC for S. aureus (62.5µg/ml). P.graveolens and C.hyalolepis had lowest MIC for S. epidermis (31.25µg/ml). The previous extracts showed equal MIC against E. coli (62.5µg/ml), except P. olereaca had MIC 125µg/m, While C. hyalolepis, R. damascena had less MIC (62.5µg/ml) against P. aeruginosa. Finally, C. hyalolepis was most effective against K. pneumonia and the MIC was (62.5µg/ml). Conclusion: The results indicate moderate antibacterial activity against bacterial strains, suggesting that these plants could help us develop new medications for healing burns, in addition to their skin regenerative properties.