Mesenchymal Stem Cell Secretome Effectiveness in Healing Chronic Tendon Injury: Procollagen Analysis and Histopathology in Rat Tendons
The MSC secretome, particularly the combination of TDSCs and ASCs, may accelerate collagen Type I synthesis and improve tendon microstructure. This suggests their potential for treating chronic tendon injuries. However, further research with longer observation periods and clinical trials is crucial to confirm these findings and advance our understanding of tendon healing.
Authors
- Warsinggih Warsinggih (ORCID: https://orcid.org/0000-0002-1756-9039)
- Andi Alfian Zainuddin (ORCID: https://orcid.org/0000-0003-4436-3906)
- M. Ruksal Saleh (ORCID: https://orcid.org/0009-0002-1544-3077)
- Muhammad Andry Usman (ORCID: https://orcid.org/0000-0002-0287-1737)
- Andi Dhedie Prasatia Sam
- Muhammad Sakti (ORCID: https://orcid.org/0000-0003-2794-9884)
- Andi Firman Mubarak (ORCID: https://orcid.org/0000-0003-1042-7182)
- Heri Suroto (ORCID: https://orcid.org/0000-0002-9384-897X)
- Muhammad Phetrus Johan (ORCID: https://orcid.org/0000-0002-5567-4710)
Institutions
- Universitas Airlangga (ID)
- Universitas Muslim Indonesia (ID)
- Hasanuddin University (ID)
Publication Details
- Journal
- Stem Cells and Cloning Advances and Applications
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/sccaa.s512079
- Citations
- 2
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- Universitas Airlangga
- Lembaga Pengelola Dana Pendidikan