Development and Validation of a Predictive Nomogram for Myelosuppression Risk in Chronic Hepatitis B Patients Treated with Peginterferon

Lower BMI, WBC counts, GLB, and higher SCR levels are independent risk factors for myelosuppression among Peg-IFN-treated CHB patients. The predictive nomogram, based on those factors, is able to identify high-risk individuals for myelosuppression, thereby aiding in early alleviation of this side-effect.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-04-01
DOI
https://doi.org/10.2147/idr.s508538
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and Validation of a Predictive Nomogram for Myelosuppression Risk in Chronic Hepatitis B Patients Treated with Peginterferon

Zhilong Wen, Pei Shi, Jiwei Fu, Wentao Zhu et al.
Infection and Drug Resistance
Hepatitis C virus research
article

Development and Validation of a Predictive Nomogram for Myelosuppression Risk in Chronic Hepatitis B Patients Treated with Peginterferon

Zhilong Wen, Pei Shi, Jiwei Fu, Wentao Zhu, Mengyu Tao, Ting Deng, Xiaoping Wu, Ting Zheng
article en

Abstract

Lower BMI, WBC counts, GLB, and higher SCR levels are independent risk factors for myelosuppression among Peg-IFN-treated CHB patients. The predictive nomogram, based on those factors, is able to identify high-risk individuals for myelosuppression, thereby aiding in early alleviation of this side-effect.

Infection and Drug ResistanceVol. Volume 18
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN), First Affiliated Hospital of Nanchang University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Hepatitis C virus research
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