The Buerger’s Disease and the Type I Cryoglobulinemia,T Entities Expression of the Same Type III Hypersensitivity Reaction

The type I cryoglobulinemia vasculitis is a life-threatening disorder because of the severity of cutaneous and renal involvement and the underlying hemopathy and even a limited quantity of paraproteins can cause severe symptoms and the Type I cryoglobulinemia accounts for 10%–15% of patients with cryoglobulinemia. Thromboangiitis obliterans, (formely called Buerger disease), is an uncommon cause of vasculitis, that affects the small to medium-sized arteries and veins of the extremities (upper and lower) and, less commonly, cerebral/visceral vessels with a nonatherosclerotic, segmental, inflammatory disease.