Noninvasive Temporal Interference Stimulation of the Subthalamic Nucleus in Parkinson's Disease Reduces Beta Activity
TIS has the potential to effectively modulate the STN and reduce the beta oscillatory activity in a completely noninvasive manner, as is traditionally possible only with intracranial DBS. Future studies should confirm the clinical effectiveness of TIS and determine whether TIS could be used to identify optimal DBS candidates and individualize DBS targets. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Florian Missey (ORCID: https://orcid.org/0000-0002-8386-0377)
- Martin Lamoš (ORCID: https://orcid.org/0000-0003-1276-4342)
- Irena Rektorová (ORCID: https://orcid.org/0000-0002-5455-4573)
- Adam Williamson (ORCID: https://orcid.org/0000-0002-5632-0084)
- Pavel Daniel
- Antonino M. Cassarà (ORCID: https://orcid.org/0000-0003-3375-7440)
- Eric Daniel Głowacki (ORCID: https://orcid.org/0000-0002-0280-8017)
- Jan Trajlínek
- Viktor Jirsa (ORCID: https://orcid.org/0000-0002-8251-8860)
- Martina Bočková (ORCID: https://orcid.org/0000-0003-2691-9122)
- Radim Jančálek (ORCID: https://orcid.org/0000-0001-6834-6567)
- Mariane de Araújo e Silva
- Esra Neufeld (ORCID: https://orcid.org/0000-0001-5528-6147)
- Ondřej Studnička
- Jan Chrastina (ORCID: https://orcid.org/0000-0002-7529-773X)
- Romain Carron
- Claudia Lubrano
Institutions
- Central European Institute of Technology (CZ)
- Inserm (FR)
- Masaryk University (CZ)
- Aix-Marseille Université (FR)
- Foundation for Research on Information Technologies in Society (CH)
- Central European Institute of Technology – Masaryk University (CZ)
- University Hospital Brno (CZ)
- Institut de Neurosciences des Systèmes (FR)
- St. Anne's University Hospital Brno (CZ)
- Brno University of Technology (CZ)
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1002/mds.30134
- Citations
- 28
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 38.90
Funders
- National Science Foundation
- European Commission
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Grantová Agentura České Republiky
- Ministerstvo Zdravotnictví Ceské Republiky
- HORIZON EUROPE Framework Programme