Elevated <scp>CD47</scp> Expression Impairs Elimination of Photoaged Fibroblasts by Macrophages and Serves as a Potential Biomarker for Photoaging
The present study demonstrated for the first time that CD47 was highly expressed and involved in mediating photoaged fibroblasts accumulation, providing important evidence for CD47 as a potential biomarker and therapeutic target for photoaging.
Authors
- Xinling Chen (ORCID: https://orcid.org/0000-0002-8442-0592)
- Lai Wei (ORCID: https://orcid.org/0000-0003-1000-7559)
- Xinya Xu (ORCID: https://orcid.org/0000-0002-3631-0428)
- Amin Yao (ORCID: https://orcid.org/0000-0002-2813-6204)
- Xinhua Lu (ORCID: https://orcid.org/0000-0001-9120-0013)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/jocd.70098
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China