Immunohistochemical‐Based Molecular Typing of <scp>ACRG</scp> Combined With Immune‐Associated <scp>PD</scp>‐<scp>L1</scp> Expression Can Predict the Prognosis of Gastric Cancer
The combination of ACRG molecular subtyping and PD-L1 expression serves as an effective predictor of GC prognosis, facilitating tailored clinical decision-making. The ACRG-PD-L1 classification system offers a practical, cost-effective approach for routine clinical application, providing critical insight into GC heterogeneity. Further multicenter studies are needed to validate these findings and explore the impact of ACRG subtypes on therapy responses, particularly in immunotherapy settings.
Authors
- Yueping Liu (ORCID: https://orcid.org/0000-0002-4582-114X)
- Huirui Zhang
- Xiaoxiao Wang (ORCID: https://orcid.org/0000-0002-3712-9823)
- Zihao Chen (ORCID: https://orcid.org/0000-0003-3924-6350)
- Jiankun He
- Zeqing Hu (ORCID: https://orcid.org/0009-0005-8168-5404)
- Huiyan Deng (ORCID: https://orcid.org/0000-0002-5499-8991)
- Fang Li (ORCID: https://orcid.org/0000-0002-4100-3684)
Institutions
- Hebei Medical University (CN)
- Kunming Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Jiangxi Pingxiang People's Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/cam4.70863
- Citations
- 2
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.04