Plasma‐Derived Exosomal <scp>i‐tRF‐LeuCAA</scp> as Biomarker for Glioma Diagnosis and Promoter of Epithelial‐Mesenchymal Transition via <scp>TPM4</scp> Regulation
i-tRF-LeuCAA could be served as a non-invasive biomarker in the diagnosis and prognosis of glioma. i-tRF-LeuCAA may indirectly regulate TPM4 expression and influence epithelial-mesenchymal transition, which may promote glioma progression.
Authors
- Hongyu Liu (ORCID: https://orcid.org/0000-0002-1571-0385)
- Jialin Liu (ORCID: https://orcid.org/0000-0001-6625-3076)
- Wentao Hu (ORCID: https://orcid.org/0000-0002-4008-2034)
- Ze Li (ORCID: https://orcid.org/0000-0001-6918-9620)
- Ling Chen (ORCID: https://orcid.org/0009-0008-6671-0204)
- Lijun Zhang (ORCID: https://orcid.org/0000-0003-4974-2745)
Institutions
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
- Hainan General Hospital (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/cns.70356
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China