NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025
The NCCN Guidelines for Testicular Cancer provide recommendations for the multidisciplinary approach to the diagnostic workup, treatment, and follow-up for testicular germ cell tumors, including both seminoma and nonseminoma. These NCCN Guidelines Insights discuss the current treatment recommendations and supporting clinical data for seminomas as presented in Version 2.2025 of the NCCN Guidelines for Testicular Cancer.
Authors
- Laura Graham (ORCID: https://orcid.org/0000-0003-4371-572X)
- Benjamin Louis Maughan (ORCID: https://orcid.org/0000-0002-0010-8551)
- Hamid Emamekhoo (ORCID: https://orcid.org/0000-0002-8506-8703)
- Jean‐Claude M. Rwigema (ORCID: https://orcid.org/0000-0003-2180-1280)
- Timothy D. Gilligan (ORCID: https://orcid.org/0000-0003-2308-9303)
- Ankeet Shah (ORCID: https://orcid.org/0000-0001-5073-3016)
- Phillip M. Pierorazio (ORCID: https://orcid.org/0000-0003-0766-9981)
- Daniel M. Geynisman (ORCID: https://orcid.org/0000-0002-1423-5295)
- Joel Picus (ORCID: https://orcid.org/0000-0002-4038-936X)
- Harshraj Leuva
- Paul Monk (ORCID: https://orcid.org/0000-0002-0508-2987)
- Kanishka Sircar (ORCID: https://orcid.org/0000-0001-9515-697X)
- Bailee Sliker (ORCID: https://orcid.org/0000-0002-4686-4221)
- Alexandra Drakaki (ORCID: https://orcid.org/0000-0001-8865-3548)
- Soroush Rais‐Bahrami (ORCID: https://orcid.org/0000-0001-9466-9925)
- Nabil Adra (ORCID: https://orcid.org/0000-0001-8905-8329)
- Thenappan Chandrasekar (ORCID: https://orcid.org/0000-0002-2173-5028)
- Scott E. Eggener (ORCID: https://orcid.org/0000-0001-6677-2503)
- Nirmish Singla
- Kosj Yamoah (ORCID: https://orcid.org/0000-0001-9055-3538)
- Bradley A. McGregor (ORCID: https://orcid.org/0000-0002-8298-0289)
- Philip J. Saylor (ORCID: https://orcid.org/0000-0003-4849-3695)
- Peter A. Humphrey (ORCID: https://orcid.org/0009-0006-9958-9717)
- Sarah Montgomery (ORCID: https://orcid.org/0000-0002-4189-5416)
- Aditya Bagrodia (ORCID: https://orcid.org/0000-0002-3358-1193)
- Daniel Wei Lin (ORCID: https://orcid.org/0000-0002-2135-1534)
- Daniel N. Costa (ORCID: https://orcid.org/0000-0002-2890-5720)
- David James VanderWeele (ORCID: https://orcid.org/0000-0003-4576-5034)
- Amy N. Luckenbaugh (ORCID: https://orcid.org/0000-0001-6598-9372)
- Rahul Aggarwal (ORCID: https://orcid.org/0000-0001-7003-7982)
- Ali Zhumkhawala
- Zachery R. Reichert (ORCID: https://orcid.org/0000-0003-0356-8796)
- Darren R. Feldman
- Sumit Shah
- Ellis G. Levine
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- City Of Hope National Medical Center (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Dana-Farber Brigham Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2025-04-01
- DOI
- https://doi.org/10.6004/jnccn.2025.0018
- Citations
- 14
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 28.09
Funders
- AstraZeneca
- National Comprehensive Cancer Network
- Janssen Scientific Affairs
- Springworks Therapeutics
- Coherus Biosciences
- Janssen Biotech