A Bench‐Stable Fluorophosphine Nickel(0) Complex and Its Catalytic Application
We herein present a fluorophosphine-based nickel(0) complex [Ni(PFPh<sub>2</sub>)<sub>4</sub>] (1), which is highly stable in air and water. [Ni(PFPh<sub>2</sub>)<sub>4</sub>] can be obtained from a one-pot reaction of [Ni(MeCN)<sub>4</sub>](BF<sub>4</sub>)<sub>2</sub> with Ph<sub>2</sub>P(═O)-PPh<sub>2</sub>, involving a unique in situ reduction of Ni(II) to Ni(0) and a simultaneous fluorination by the BF<sub>4</sub> <sup>-</sup> anion. This complex does not only incorporate a nickel center in the zero-oxidation state, resulting from a Ni(II) precursor, but also includes fluorophosphine ligands, which typically disproportionate immediately in solution. The application of [Ni(PFPh<sub>2</sub>)<sub>4</sub>] as highly stable Ni(0) pre-catalyst in combination with additional phosphine ligands, such as dppf (1,1'-bis(diphenylphosphino)ferrocene), in various coupling reactions uncovers its high catalytic activity and versatility, which is superior to [Ni(COD)<sub>2</sub>] (COD═cycloocta-1,5-diene) as conventional Ni(0) source.
Authors
- Arjun Neyyathala (ORCID: https://orcid.org/0000-0001-5161-4801)
- Toni Grell (ORCID: https://orcid.org/0000-0001-9162-6487)
- Franziska Flecken (ORCID: https://orcid.org/0000-0003-4418-7455)
- Schirin Hanf (ORCID: https://orcid.org/0000-0003-2624-7872)
Institutions
- Karlsruhe Institute of Technology (DE)
- University of Milan (IT)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1002/anie.202506271
- Citations
- 5
- Primary Topic
- Asymmetric Hydrogenation and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 2.69
Funders
- Deutsche Forschungsgemeinschaft
- Stiftung der Deutschen Wirtschaft