Quality by design-based optimization and HP-TLC densitometric standardization of Theobroma cacao L. extract as a nutraceutical supplement
In conclusion, the novel, validated HP-TLC method simultaneously detects EGCG and CTN in the cocoa extract. Tablets formulated by direct compression are safe as nutraceuticals and hold promise as supplements in palliative cancer therapy.
Authors
- Priyanka Patil (ORCID: https://orcid.org/0000-0002-3402-9114)
- Vishal S. Patil (ORCID: https://orcid.org/0000-0002-1219-1962)
- Subarna Roy (ORCID: https://orcid.org/0000-0002-6594-8615)
- Vinayak Mastiholimath (ORCID: https://orcid.org/0000-0002-8560-4705)
- Darasaguppe R. Harish
- Harsha V. Hegde (ORCID: https://orcid.org/0000-0002-9890-6745)
- Atith Muppayyanamath
Institutions
- KLE Academy of Higher Education and Research (IN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fnut.2025.1537963
- Citations
- 3
- Primary Topic
- Food Chemistry and Fat Analysis
- Type
- article
- Field-Weighted Citation Impact
- 3.49