White Cord Syndrome Following Anterior Cervical Discectomy and Fusion: A Case of Transient Quadriplegia With Complete Neurological Recovery

Cervical myelopathy is a progressive degenerative condition characterized by spinal cord compression, which often requires surgery to avoid further stepwise deterioration of this pathology. While anterior cervical discectomy and fusion (ACDF) is a well-established treatment, postoperative neurological deficits, although rare, remain a significant concern. White cord syndrome (WCS) is an uncommon cause of acute neurological deficit following spine surgery that is attributed to a reperfusion injury following decompression of a chronically impinged spinal cord. We present the case of a 47-year-old male with a preoperative diagnosis of cervical myelopathy (Nurick 4) who developed acute quadriplegia following ACDF. Initial imaging ruled out common postoperative complications, such as hematoma or hardware malposition, and an MRI revealed hyperintense signals consistent with WCS. Supportive management led to partial neurological recovery by postoperative day 3, followed by complete neurological recovery and marked functional and strength improvement beyond baseline by the five-month follow-up. This report aims to present a case of WCS, a rare complication following spinal decompression surgery, highlighting its diagnosis, management, and outcome.

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Journal
Cureus
Published
2025-04-09
DOI
https://doi.org/10.7759/cureus.81961
Primary Topic
Cervical and Thoracic Myelopathy
Type
article
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article

White Cord Syndrome Following Anterior Cervical Discectomy and Fusion: A Case of Transient Quadriplegia With Complete Neurological Recovery

J.C. Regueiro López, Felix Rivera Troia
1 links
Cureus
Cervical and Thoracic Myelopathy
article

White Cord Syndrome Following Anterior Cervical Discectomy and Fusion: A Case of Transient Quadriplegia With Complete Neurological Recovery

J.C. Regueiro López, Felix Rivera Troia
article en

Abstract

Cervical myelopathy is a progressive degenerative condition characterized by spinal cord compression, which often requires surgery to avoid further stepwise deterioration of this pathology. While anterior cervical discectomy and fusion (ACDF) is a well-established treatment, postoperative neurological deficits, although rare, remain a significant concern. White cord syndrome (WCS) is an uncommon cause of acute neurological deficit following spine surgery that is attributed to a reperfusion injury following decompression of a chronically impinged spinal cord. We present the case of a 47-year-old male with a preoperative diagnosis of cervical myelopathy (Nurick 4) who developed acute quadriplegia following ACDF. Initial imaging ruled out common postoperative complications, such as hematoma or hardware malposition, and an MRI revealed hyperintense signals consistent with WCS. Supportive management led to partial neurological recovery by postoperative day 3, followed by complete neurological recovery and marked functional and strength improvement beyond baseline by the five-month follow-up. This report aims to present a case of WCS, a rare complication following spinal decompression surgery, highlighting its diagnosis, management, and outcome.

CureusVol. 17(4)
Ponce Health Sciences University (PR)
Openalex Percentile: Top 88%
Cervical and Thoracic Myelopathy
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White Cord Syndrome Following Anterior Cervical Discectomy and Fusion: A Case of Transient Quadriplegia With Complete Neurological Recovery — J.C. Regueiro López, Felix Rivera Troia · Cureus (2025) | TGRS Research Map | TGRS