Targeting bladder cancer: Potent anti-cancer effects of cannabichromene and delta-9-tetrahydrocannabinol-rich Cannabis sativa strains
The findings suggest that <i>C. sativa</i> strains PARIS, DQ, and sCBD, containing CBC and THC, exhibit significant anticancer activity against UC cell lines and <i>ex vivo</i> models. These results underscore the therapeutic potential of CBC- and THC-rich <i>C. sativa</i> extracts in bladder cancer treatment.
Authors
- Sukumaran Anil (ORCID: https://orcid.org/0000-0002-6440-8780)
- Omer Anis (ORCID: https://orcid.org/0000-0002-9500-7584)
- Yaron Shav‐Tal (ORCID: https://orcid.org/0000-0002-8017-948X)
- Adi Zundelevich (ORCID: https://orcid.org/0000-0001-6629-3588)
- Vered Bar
- Zohar Dotan (ORCID: https://orcid.org/0000-0002-9005-2992)
- Tomer Drori (ORCID: https://orcid.org/0000-0001-6334-4554)
- Alon Lazarovich (ORCID: https://orcid.org/0000-0002-7521-5319)
- Dan Dominissini (ORCID: https://orcid.org/0000-0003-1121-5130)
- Hinanit Koltai (ORCID: https://orcid.org/0000-0003-2818-2160)
- Menachem Laufer
- Gil Raviv
- Amos Toren
- Jacob Ramon
Institutions
- Bar-Ilan University (IL)
- Tel Aviv University (IL)
- Sheba Medical Center (IL)
- Agricultural Research Organization (IL)
- Applied Materials (Israel) (IL)
- Institute for Female Pelvic Medicine and Reconstructive Surgery (US)
Publication Details
- Journal
- Asian journal of urology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1016/j.ajur.2025.03.004
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00