Chronic Stress Stimulates Protumor Macrophage Polarization to Propel Lung Cancer Progression
Chronic stress facilitates lung cancer immune evasion by inducing M2-like macrophage polarization, supporting the potential of combination therapies targeting both tumor cells and the immune microenvironment for treating stress-related cancers.
Authors
- Fei Wang (ORCID: https://orcid.org/0009-0008-6141-4529)
- Bingjie Cui (ORCID: https://orcid.org/0000-0002-5912-0344)
- Yong Yu (ORCID: https://orcid.org/0000-0003-1928-2514)
- Ruiqi Hu
- Clemens A. Schmitt (ORCID: https://orcid.org/0000-0002-4731-2226)
- Jing Du
- Ran Gao (ORCID: https://orcid.org/0000-0001-8712-429X)
- Jingjing Qi (ORCID: https://orcid.org/0000-0003-2096-7406)
- Jiong Deng (ORCID: https://orcid.org/0000-0002-4489-7556)
- Guoxing Yu
- Hongliang Dong (ORCID: https://orcid.org/0000-0001-6165-0849)
- Qian Zhang
- Chen Li (ORCID: https://orcid.org/0000-0001-5385-6249)
- Cuilan Liu (ORCID: https://orcid.org/0000-0003-4879-7445)
- Weiwei Chen (ORCID: https://orcid.org/0009-0004-5380-7075)
- Haina Du
Institutions
- Qingdao University (CN)
- Johannes Kepler University of Linz (AT)
- Helmholtz Association of German Research Centres (DE)
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Max Delbrück Center (DE)
- Humboldt-Universität zu Berlin (DE)
- Kepler Universitätsklinikum (AT)
- Qingdao Municipal Hospital (CN)
- Institute of Laboratory Animal Science (CN)
- Qingdao Eighth People's Hospital (CN)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Cancer Research
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1158/0008-5472.can-24-3481
- Citations
- 11
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 10.30