Influence of race, ethnicity, and sex on the performance of epigenetic predictors of phenotypic traits
We found evidence for substantial disparities in epigenetic predictor performance, with each predictor exhibiting at least one significant difference in correlation or MAE related to race, ethnicity, or sex.
Authors
- Jamaji C. Nwanaji‐Enwerem (ORCID: https://orcid.org/0000-0003-0356-4867)
- Nicole Gladish (ORCID: https://orcid.org/0000-0001-6039-7001)
- Belinda L. Needham (ORCID: https://orcid.org/0000-0001-5939-2027)
- Saher Daredia (ORCID: https://orcid.org/0000-0002-7906-4087)
- Dennis Khodasevich (ORCID: https://orcid.org/0000-0003-1412-8251)
- Andrés Cárdenas (ORCID: https://orcid.org/0000-0003-2284-3298)
- Hanyang Shen (ORCID: https://orcid.org/0000-0003-3273-9777)
- Anne K. Bozack (ORCID: https://orcid.org/0000-0003-0046-5767)
- David H. Rehkopf (ORCID: https://orcid.org/0000-0002-7597-6513)
Institutions
- Palo Alto University (US)
- VA Palo Alto Health Care System (US)
- University of Michigan (US)
- Stanford Health Care (US)
- Center for Health Justice (US)
- Berkeley Public Health Division (US)
- University of Pennsylvania (US)
- University of California, Berkeley (US)
- Stanford University (US)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1186/s13148-025-01864-6
- Citations
- 7
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- National Institute on Aging
- National Institute of Environmental Health Sciences
- National Institute on Minority Health and Health Disparities