Antigen masking indirect antiglobulin test can mitigate the interference of Mezagitamab, a novel anti‐<scp>CD38</scp> antibody, in serological pre‐transfusion testing

All novel anti-CD38 antibodies, such as mezagitamab, have the potential to interfere in serological pre-transfusion testing. While masking only one epitope, DaraEx has so far been an effective mitigation for all clinical anti-CD38 antibodies.

Authors

Publication Details

Journal
Transfusion Medicine
Published
2025-04-09
DOI
https://doi.org/10.1111/tme.13139
Citations
1
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
1.82
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article

Antigen masking indirect antiglobulin test can mitigate the interference of Mezagitamab, a novel anti‐CD38 antibody, in serological pre‐transfusion testing

Cora P. Habicht, Clemens Schneeweiß
1 citations
Transfusion Medicine
Blood disorders and treatments
1.82
article

Antigen masking indirect antiglobulin test can mitigate the interference of Mezagitamab, a novel anti‐CD38 antibody, in serological pre‐transfusion testing

Cora P. Habicht, Clemens Schneeweiß
article en
1 citations

Abstract

All novel anti-CD38 antibodies, such as mezagitamab, have the potential to interfere in serological pre-transfusion testing. While masking only one epitope, DaraEx has so far been an effective mitigation for all clinical anti-CD38 antibodies.

Transfusion MedicineVol. 35(4)
Good health and well-being
Openalex Percentile: Top 17%
Blood disorders and treatments
1.82
DOIOpen Access PDFOpenAlex
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Antigen masking indirect antiglobulin test can mitigate the interference of Mezagitamab, a novel anti‐<scp>CD38</scp> antibody, in serological pre‐transfusion testing — Cora P. Habicht, Clemens Schneeweiß · Transfusion Medicine (2025) | TGRS Research Map | TGRS