Enantioselective catalytic Urech hydantoin synthesis
The first catalytic enantioselective Urech synthesis is developed via organocatalytic desymmetrization and kinetic resolution. Using easily available malonic esters and isothiocyanates as substrates, various hydantoins with aza-quaternary stereocenters are formed under simple conditions.
Authors
- Zhuo‐Chen Li
- Yu‐Ping He
- Xing-Zi Li
- Hua Yue Wu (ORCID: https://orcid.org/0000-0002-0401-2434)
- Abudu Rexit Abulikemu
- Ziqi Wang (ORCID: https://orcid.org/0000-0002-4353-2176)
- Wen-Ya Zheng
Institutions
- Shanghai University (CN)
- Xinjiang Normal University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Innovative Research Center of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00378d
- Citations
- 3
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 2.42