Mineralization of macroaggregated albumin for accurate biodistribution evaluation of pre-radiotherapy
Conventional macroaggregated albumin (MAA) often fails to accurately simulate the biodistribution of <sup>90</sup>Y microspheres in hepatic artery perfusion scintigraphy due to density mismatch. By mineralizing MAA, we developed lightly mineralized MAA (L-MAA) and highly mineralized MAA (H-MAA) with controlled densities, which enabled more accurate simulation of the biodistribution of resin and glass microspheres.
Authors
- Yu Yuan (ORCID: https://orcid.org/0000-0003-1032-6330)
- Mingru Zhang (ORCID: https://orcid.org/0000-0002-4514-9824)
- Dongping Fang (ORCID: https://orcid.org/0000-0002-1971-9045)
- Kuikun Yang (ORCID: https://orcid.org/0000-0001-7451-1813)
- Shaolong Qi (ORCID: https://orcid.org/0000-0003-2744-5387)
- Meiqi Cheng (ORCID: https://orcid.org/0009-0001-8404-3408)
- Shoujun Zhu (ORCID: https://orcid.org/0000-0002-2412-6121)
- Fei Kang (ORCID: https://orcid.org/0000-0003-0267-7819)
- Xiaomin Gao
- Guocan Yu (ORCID: https://orcid.org/0000-0003-1157-4184)
- Xiaohua Yu (ORCID: https://orcid.org/0000-0003-3341-8377)
Institutions
- Zhejiang Sci-Tech University (CN)
- Jilin University (CN)
- Harbin Institute of Technology (CN)
- Xijing Hospital (CN)
- Heilongjiang Institute of Technology (CN)
- State Key Laboratory of Supramolecular Structure and Materials
- Tsinghua University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc01204j
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00