Analysis of differentially expressed genes in schizophrenia based on bioinformatics and corresponding mRNA expression levels

This study identified several DEGs potentially linked to the pathogenesis of schizophrenia, suggesting that HDAC1, UBA52, and FYN could serve as candidate susceptibility genes and diagnostic biomarkers. These findings provide new insights and directions for future schizophrenia research.

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Publication Details

Journal
Schizophrenia Research
Published
2025-04-09
DOI
https://doi.org/10.1016/j.schres.2025.04.002
Citations
2
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
3.63
Controls
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article

Analysis of differentially expressed genes in schizophrenia based on bioinformatics and corresponding mRNA expression levels

Shiqi Tian, Fang Liu, Zhaowei Teng, Xiaoying Liu et al.
2 citations
Schizophrenia Research
Genetic Associations and Epidemiology
3.63
article

Analysis of differentially expressed genes in schizophrenia based on bioinformatics and corresponding mRNA expression levels

Shiqi Tian, Fang Liu, Zhaowei Teng, Xiaoying Liu, Zhiwei Tang, Hu Zhang, Meiting Liu
article en
2 citations

Abstract

This study identified several DEGs potentially linked to the pathogenesis of schizophrenia, suggesting that HDAC1, UBA52, and FYN could serve as candidate susceptibility genes and diagnostic biomarkers. These findings provide new insights and directions for future schizophrenia research.

Schizophrenia ResearchVol. 280
Army Medical University (CN), Dalian Medical University (CN), Sichuan University (CN), Kunming Medical University (CN), West China Hospital of Sichuan University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), First Affiliated Hospital of Kunming Medical University (CN), Sixth Affiliated Hospital of Kunming Medical University (CN), Chongqing Medical University (CN)
Zero hunger
Openalex Percentile: Top 9%
Genetic Associations and Epidemiology
3.63
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Analysis of differentially expressed genes in schizophrenia based on bioinformatics and corresponding mRNA expression levels — Shiqi Tian, Fang Liu, et al. · Schizophrenia Research (2025) | TGRS Research Map | TGRS