Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate stratification of patients with extrahepatic cholangiocarcinoma
Single-cell transcriptomic analysis reveals prognosis-related stromal signatures that potentiate the stratification of eCCA into proliferative, inflammatory and fibrotic, and neuronal phenotypes, which has important implications on molecular classification and exploring therapeutic targets in eCCA.
Authors
- Wenlong Zhai (ORCID: https://orcid.org/0000-0003-2559-2105)
- Xiaohan Yao
- Dekang Lv
- Zhihai Qin (ORCID: https://orcid.org/0000-0001-9793-7964)
- Rulin Hua
- Linlin Wang (ORCID: https://orcid.org/0000-0002-0558-3052)
- Anqi Li (ORCID: https://orcid.org/0000-0003-3182-1971)
- Ni Chen (ORCID: https://orcid.org/0000-0002-0628-0723)
- Ruo Feng (ORCID: https://orcid.org/0000-0002-6081-8635)
- Yuanyuan Yang (ORCID: https://orcid.org/0000-0002-0623-636X)
- Yu Long (ORCID: https://orcid.org/0009-0003-9672-6593)
- Jialu Liang
- Wentao Liu (ORCID: https://orcid.org/0009-0008-9257-8155)
Institutions
- Dalian Medical University (CN)
- Zhengzhou University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1186/s12876-025-03829-8
- Citations
- 3
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- National Natural Science Foundation of China