Putative function and prognostic molecular marker of mast cells in colorectal cancer
This study identified the cell types within CRC, elaborated the cellular functions of mast cells in CRC development and their molecular communication to coordinate malignant cells, and highlighted the molecular components and biological features that constitute promising prognostic classification model.
Authors
- Ke Xu (ORCID: https://orcid.org/0000-0003-1458-8741)
- Zengjie Lei (ORCID: https://orcid.org/0000-0001-8961-3214)
- Mengxi Huang (ORCID: https://orcid.org/0000-0002-9274-6023)
- Jiani Guo (ORCID: https://orcid.org/0000-0002-9899-0924)
- Hongyu Wang (ORCID: https://orcid.org/0000-0001-5720-6542)
- Xiaoyuan Chu (ORCID: https://orcid.org/0000-0002-7917-7874)
- Xiaoming Bai (ORCID: https://orcid.org/0000-0003-4372-5653)
- Haimei Feng
- Yi‐Ting Wang (ORCID: https://orcid.org/0000-0003-2008-4435)
- Jie Chen (ORCID: https://orcid.org/0009-0007-5432-8465)
- Siqi Sheng
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1186/s12920-025-02117-4
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Jiangsu Commission of Health
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation