Pregnancy After Fertility Sparing Surgery in Advanced Ovarian Low-grade Papillary Serous Carcinoma: A Case Report

Ovarian Low-grade serous carcinoma (LGSC), a type of epithelial ovarian tumor, is often diagnosed in the advanced stage. Treatment involves surgery and chemotherapy. In advanced stages (3 and 4), removing all tumoral implants with both the uterus and ovaries (debunking surgery) is the first surgical goal. We presented a case of a 38-year-old woman who became pregnant three years after being diagnosed with LGSOC at stage 3c. We resected all tumoral implants, and decision was made to preserve the uterus for her since the patient wanted to be pregnant. The patient underwent surgery, then followed by a standard chemotherapy regime. During the three years of follow-up, there were no signs of tumor return; she decided to get pregnant by egg donation through an in vitro fertilization (IVF) procedure. A cesarean section was done, and the twin infants were born in good condition and with good APGAR scores.

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Publication Details

Journal
Journal of Obstetrics Gynecology and Cancer Research
Published
2025-03-13
DOI
https://doi.org/10.30699/jogcr.10.5.424
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Pregnancy After Fertility Sparing Surgery in Advanced Ovarian Low-grade Papillary Serous Carcinoma: A Case Report

Elham Sharafkhani, Hamid Mollazadeh, Malihe Hasanzadeh, Mohammad Montazami Sadeghi
Journal of Obstetrics Gynecology and Cancer Research
Ovarian cancer diagnosis and treatment
article

Pregnancy After Fertility Sparing Surgery in Advanced Ovarian Low-grade Papillary Serous Carcinoma: A Case Report

Elham Sharafkhani, Hamid Mollazadeh, Malihe Hasanzadeh, Mohammad Montazami Sadeghi
article en

Abstract

Ovarian Low-grade serous carcinoma (LGSC), a type of epithelial ovarian tumor, is often diagnosed in the advanced stage. Treatment involves surgery and chemotherapy. In advanced stages (3 and 4), removing all tumoral implants with both the uterus and ovaries (debunking surgery) is the first surgical goal. We presented a case of a 38-year-old woman who became pregnant three years after being diagnosed with LGSOC at stage 3c. We resected all tumoral implants, and decision was made to preserve the uterus for her since the patient wanted to be pregnant. The patient underwent surgery, then followed by a standard chemotherapy regime. During the three years of follow-up, there were no signs of tumor return; she decided to get pregnant by egg donation through an in vitro fertilization (IVF) procedure. A cesarean section was done, and the twin infants were born in good condition and with good APGAR scores.

Journal of Obstetrics Gynecology and Cancer ResearchVol. 10(5)
Mashhad University of Medical Sciences (IR), North Khorasan University of Medical Sciences (IR)
Openalex Percentile: Top 89%
Ovarian cancer diagnosis and treatment
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