Rational design of alternative treatment options for radioresistant rectal cancer using patient-derived organoids

Combining RRx-001 with the inhibition of GCLC may be a promising alternative treatment strategy in radioresistant rectal cancer.

Authors

Bastiaan J. Viergever (ORCID: https://orcid.org/0000-0001-7281-5872)
Onno Kranenburg (ORCID: https://orcid.org/0000-0002-2112-4390)
Martijn Intven (ORCID: https://orcid.org/0000-0002-5068-5517)
Daan Andel (ORCID: https://orcid.org/0000-0001-9858-868X)
Inne H.M. Borel Rinkes (ORCID: https://orcid.org/0000-0003-2122-7207)
Amanda Nouwens (ORCID: https://orcid.org/0000-0003-4069-8266)
Sabine Klaassen (ORCID: https://orcid.org/0000-0001-5925-9912)
André Verheem
Jeroen Hagendoorn (ORCID: https://orcid.org/0000-0001-8737-3923)
Jamila Laoukili
Maurice M.J.M. Zandvliet (ORCID: https://orcid.org/0000-0002-0542-5433)