Associations of peripheral blood lymphopenia to disease course, treatment and TNF-α in sarcoidosis
B-cell penia is common in sarcoidosis patients while T-cell penia is mainly a feature of the sarcoidosis PB lymphopenia phenotype. Increased lymphocyte counts during TNFi treatment suggests that TNF-α signaling is of importance for sarcoidosis associated lymphopenia.
Authors
- Susanna Kullberg (ORCID: https://orcid.org/0000-0003-2844-4773)
- Gustav Hallén
- Clas Malmeström (ORCID: https://orcid.org/0000-0003-2477-0088)
- Anna Smed‐Sörensen (ORCID: https://orcid.org/0000-0001-6966-7039)
- Avinash Padhi (ORCID: https://orcid.org/0000-0002-5545-3598)
- Elina Erikson
- Anders Eklúnd (ORCID: https://orcid.org/0000-0002-7263-7057)
Institutions
- Karolinska University Hospital (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1186/s12931-025-03212-x
- Primary Topic
- Sarcoidosis and Beryllium Toxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00