Diagnostic Utility of SATB2, CDX2, CD10, and β-Catenin Immunohistochemistry in WNT Pathway–Altered Odontogenic Tumors
This study presents novel findings on the immunoreactivity of intestinal markers SATB2 and CDX2 in WNT-OTs. SATB2 is a sensitive and specific marker for the diagnosis of WNT-OTs, and CDX2 and CD10 may serve as additional markers for WNT-OTs. Additionally, the immunohistochemical similarities between DGCT and AA further support the view that these 2 tumors represent the histologic spectrum of the same entity.
Authors
- Hye‐Jung Yoon (ORCID: https://orcid.org/0000-0002-3534-3295)
- Kyu‐Young Oh (ORCID: https://orcid.org/0000-0001-5328-0905)
- Ji‐hoon Kim (ORCID: https://orcid.org/0000-0002-6349-6950)
Institutions
- Seoul National University (KR)
- Duke University (US)
- Seoul National University Dental Hospital (KR)
- Dankook University (KR)
Publication Details
- Journal
- Archives of Pathology & Laboratory Medicine
- Published
- 2025-04-09
- DOI
- https://doi.org/10.5858/arpa.2024-0416-oa
- Citations
- 5
- Primary Topic
- Oral and Maxillofacial Pathology
- Type
- article
- Field-Weighted Citation Impact
- 8.95
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea