Association between the generation of cephalosporins for perioperative prophylaxis and postoperative surgical site infections in open fractures: a prospective cohort study
Perioperative use of higher-generation cephalosporins was not associated with a reduction in postoperative surgical site infections in open fractures. Our study supports existing guidelines that recommend the use of first-generation cephalosporins as the preferred agents for preventing SSIs in open fractures.
Authors
- Xin Xing (ORCID: https://orcid.org/0000-0001-9486-6830)
- Yanbin Zhu
- Kuo Zhao (ORCID: https://orcid.org/0000-0003-4557-4086)
- Ziheng Peng (ORCID: https://orcid.org/0000-0002-8171-0252)
- Zhucheng Jin
- Junyong Li (ORCID: https://orcid.org/0000-0002-7438-5615)
- Zhenbang Yang
- Dandan Ye (ORCID: https://orcid.org/0000-0002-3838-8552)
- Juan Wang
- Wei Chen (ORCID: https://orcid.org/0000-0001-5451-6430)
- Ming Li (ORCID: https://orcid.org/0000-0001-9223-1508)
- Yingze Zhang (ORCID: https://orcid.org/0000-0001-8042-6105)
- Kai Ding (ORCID: https://orcid.org/0000-0002-1735-1435)
- Pei Du
- Hongzhi Lv (ORCID: https://orcid.org/0000-0003-1616-6243)
- Zhao-Hui Song
- Hongyu Meng
- Junzhe Zhang (ORCID: https://orcid.org/0000-0003-3471-037X)
Institutions
- Hebei Medical University (CN)
- Central South University (CN)
- Third Hospital of Hebei Medical University (CN)
- Plastic Surgery Hospital (CN)
- People's Hospital of Cangzhou (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1097/js9.0000000000002371
- Primary Topic
- Surgical site infection prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00