To explore the multimorbidity mechanism of coronary heart disease and ischemic stroke from “phlegm and blood stasis obstructing the Luò Màis pattern”
Coronary heart disease and ischemic stroke are common cardiovascular and cerebrovascular diseases with a high multimorbidity rate. According to the theory of traditional Chinese medicine (TCM), the phlegm and blood stasis obstructing the Luò Màis pattern is the pathological basis, and the formation of phlegm and blood stasis is the key pathological factor for cardiocerebral vascular multimorbidity, implying that the treatment of cardiocerebral vascular multimorbidity should focus on eliminating phlegm and blood stasis simultaneously. Based on the discovery of modern medicine that cardiocerebral vascular multimorbidity is mostly related to lipid deposition, inflammation, atherosclerosis, microcirculation disorders, and hemodynamics, it is believed that the core pathological features of cardiocerebral vascular multimorbidity include atherosclerosis and microcirculation disorders, coinciding with the pathological mechanism that phlegm and blood stasis are formed and then obstruct the Luò Màis in the heart and brain in TCM. This paper combined modern medicine and TCM theories, analyzed the pathogenesis of coronary heart disease and ischemic stroke from the perspective of phlegm and blood stasis obstructing the Luò Màis pattern, and discussed the multimorbidity mechanism so as to provide theoretical basis for clinical treatment.
Authors
- Jiaxin Li (ORCID: https://orcid.org/0000-0002-1681-3271)
- Longbin Dai
- Lei Yang (ORCID: https://orcid.org/0000-0002-3494-8161)
- Chi Haoran
- Gao Zhehan
- Liu Zhaihua
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- CITIC Group (China) (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Guidelines and Standards of Chinese Medicine
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1097/gscm.0000000000000062
- Citations
- 3
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.14