Meet the author: Tychele N. Turner, PhD

Dr. Tychele Turner is an assistant professor of genetics at the Washington University in St. Louis. This issue of Cell Genomics presents research from her lab in "Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer" by Ng et al. This paper used their newly developed program, 3D-CLUMP, which can perform proteome-wide significant case-control analysis and clustering of protein-coding variants related to disease. Using 3D-CLUMP, they examine how patients with mostly cancer or neurodevelopmental disorders (NDDs) are observed to have the same gene, even if the specific mutations causing them are not shared.