Ameliorative Hypoglycemic Effect of 1-DNJ via Structural Derivatization Followed by Assembly Into Selenized Nanovesicles
Our findings suggest that structural derivatization improves the oral delivery of 1-DNJ and prolongs its therapeutic effect via selenized nanovesicles, positioning <i>N</i>-1-DNJ-Se@NVs as a promising nanomedicine for diabetes management.
Authors
- Yanli Du (ORCID: https://orcid.org/0000-0002-6400-1294)
- Shuxian Ruan
- Xianyuan Zhang
- Xingwang Zhang (ORCID: https://orcid.org/0000-0002-8824-3917)
- Hao Kang (ORCID: https://orcid.org/0000-0002-6582-2895)
Institutions
- Jinan University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Meizhou City People's Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s516833
- Citations
- 1
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Anhui Provincial Department of Education
- Basic and Applied Basic Research Foundation of Guangdong Province