European screening platform for EORTC clinical trials in advanced colorectal cancer ‘SPECTAcolor’

SPECTAcolor demonstrated that recruitment to an academic screening platform is feasible and that central (quality-assured) testing may remain necessary even for commonly tested markers. SPECTAcolor has generated a clinical and molecular dataset with associated samples for >800 CRC patients for future academic research such as biomarker validation. Linking screening platforms to therapeutic trials and ensuring sustainability remain challenging.

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Institutions

Publication Details

Journal
ESMO Gastrointestinal Oncology
Published
2025-04-09
DOI
https://doi.org/10.1016/j.esmogo.2025.100168
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

European screening platform for EORTC clinical trials in advanced colorectal cancer ‘SPECTAcolor’

Elisa Fontana, Maike Collienne, Dirk Arnold, Sabine Tejpar et al.
ESMO Gastrointestinal Oncology
Colorectal Cancer Treatments and Studies
article

European screening platform for EORTC clinical trials in advanced colorectal cancer ‘SPECTAcolor’

Elisa Fontana, Maike Collienne, Dirk Arnold, Sabine Tejpar, Élena Elez, Ramón Salazar, Thierry Gorlia, Markus Moehler, Aleksandra Stevovic, Florian Lordick, Daniela Ellen Aust, Annette Stein, Marie Morfouace, B. Borelli, Dorothea Wagner, G. Folprecht, Michel Ducreux, V. Golfinopoulos, Claus Henning Köhne
article en

Abstract

SPECTAcolor demonstrated that recruitment to an academic screening platform is feasible and that central (quality-assured) testing may remain necessary even for commonly tested markers. SPECTAcolor has generated a clinical and molecular dataset with associated samples for >800 CRC patients for future academic research such as biomarker validation. Linking screening platforms to therapeutic trials and ensuring sustainability remain challenging.

ESMO Gastrointestinal OncologyVol. 8
Institut Català d'Ornitologia (ES), Universität Hamburg (DE), Sarah Cannon Research Institute (GB), Johannes Gutenberg University Mainz (DE), Heidelberg University (DE), Universitair Ziekenhuis Leuven (BE), Institut Gustave Roussy (FR), University Hospital Heidelberg (DE), Asklepios Klinik Altona (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE), Institut Català d'Oncologia (ES), University Medical Center Hamburg-Eppendorf (DE), Klinikum Oldenburg (DE), European Organisation for Research and Treatment of Cancer (BE), University Hospital Leipzig (DE), University Hospital Carl Gustav Carus (DE), Vall d'Hebron Institute of Oncology (ES), University of Turin (IT), University of Lausanne (CH)
Openalex Percentile: Top 90%
Colorectal Cancer Treatments and Studies
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