Clin‐ <scp>STAR</scp> Corner: Practice‐Changing Advances at the Interface of Gastroenterology &amp; Geriatrics

With nearly 60 million Americans aged 65 and older, gastrointestinal (GI) conditions are a leading cause of healthcare utilization in this population. Despite this, older adults remain underrepresented in GI clinical trials and research, limiting evidence-based care. This review highlights three pivotal studies addressing this gap: (1) proton pump inhibitors, which are commonly used to treat gastroesophageal reflux disease, are not associated with the later development of dementia; (2) undertreatment of chronic inflammation among older adults with inflammatory bowel disease is associated with a higher rate of adverse events compared to treatment with anti-TNF therapy, a biologic agent; (3) the majority (85%) of surveillance colonoscopies among older adults with a life expectancy of ≥ 10 years did not yield colorectal cancer, advanced dysplasia, or ≥ 3 polyps.

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Publication Details

Journal
Journal of the American Geriatrics Society
Published
2025-04-09
DOI
https://doi.org/10.1111/jgs.19467
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Clin‐ STAR Corner: Practice‐Changing Advances at the Interface of Gastroenterology & Geriatrics

Bharati D. Kochar, Adam S. Faye, Aasma Shaukat
Journal of the American Geriatrics Society
Helicobacter pylori-related gastroenterology studies
article

Clin‐ STAR Corner: Practice‐Changing Advances at the Interface of Gastroenterology & Geriatrics

Bharati D. Kochar, Adam S. Faye, Aasma Shaukat
article en

Abstract

With nearly 60 million Americans aged 65 and older, gastrointestinal (GI) conditions are a leading cause of healthcare utilization in this population. Despite this, older adults remain underrepresented in GI clinical trials and research, limiting evidence-based care. This review highlights three pivotal studies addressing this gap: (1) proton pump inhibitors, which are commonly used to treat gastroesophageal reflux disease, are not associated with the later development of dementia; (2) undertreatment of chronic inflammation among older adults with inflammatory bowel disease is associated with a higher rate of adverse events compared to treatment with anti-TNF therapy, a biologic agent; (3) the majority (85%) of surveillance colonoscopies among older adults with a life expectancy of ≥ 10 years did not yield colorectal cancer, advanced dysplasia, or ≥ 3 polyps.

Journal of the American Geriatrics SocietyVol. 73(8)
Harvard University (US), NYU Langone Health (US), Massachusetts General Hospital (US)
American College of Gastroenterology, Crohn's and Colitis Foundation, National Institute on Aging
Good health and well-being
Openalex Percentile: Top 88%
Helicobacter pylori-related gastroenterology studies
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Clin‐ <scp>STAR</scp> Corner: Practice‐Changing Advances at the Interface of Gastroenterology &amp; Geriatrics — Bharati D. Kochar, Adam S. Faye, et al. · Journal of the American Geriatrics Society (2025) | TGRS Research Map | TGRS