Clin‐ <scp>STAR</scp> Corner: Practice‐Changing Advances at the Interface of Gastroenterology & Geriatrics
With nearly 60 million Americans aged 65 and older, gastrointestinal (GI) conditions are a leading cause of healthcare utilization in this population. Despite this, older adults remain underrepresented in GI clinical trials and research, limiting evidence-based care. This review highlights three pivotal studies addressing this gap: (1) proton pump inhibitors, which are commonly used to treat gastroesophageal reflux disease, are not associated with the later development of dementia; (2) undertreatment of chronic inflammation among older adults with inflammatory bowel disease is associated with a higher rate of adverse events compared to treatment with anti-TNF therapy, a biologic agent; (3) the majority (85%) of surveillance colonoscopies among older adults with a life expectancy of ≥ 10 years did not yield colorectal cancer, advanced dysplasia, or ≥ 3 polyps.
Authors
- Bharati D. Kochar (ORCID: https://orcid.org/0000-0002-8862-1236)
- Adam S. Faye (ORCID: https://orcid.org/0000-0002-1571-5856)
- Aasma Shaukat
Institutions
- Harvard University (US)
- NYU Langone Health (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1111/jgs.19467
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American College of Gastroenterology
- Crohn's and Colitis Foundation
- National Institute on Aging