HPLC‐DAD and HPLC‐ELSD Profiling of Various Parts of Selected <i>Ficus</i> Species

Due to the scarcity of chemical data related to some Ficus species, forty-three ethanolic extracts were obtained from various parts of twelve Ficus species encompassing understudied ones. Thus, these were analyzed by high-performance liquid chromatography-diode array detection (HPLC-DAD) and HPLC-evaporative light scattering detection (HPLC-ELSD) to explore their phytochemical profiles. Overall, most of the extracts contain predominantly compounds lacking chromophore visible only in HPLC-ELSD chromatograms. However, HPLC-DAD analyses revealed furanocoumarins psoralen and bergapten to be dominant in extracts of all parts of F. carica and F. pumila, together with the extract of the leaves of F. cyathistipula. Some extracts (e.g., those from F. microcarpa and F. lyrata) displayed only peaks corresponding to chlorogenic acid and its derivatives. Remarkably, the extract of the roots of F. cyathistipula is rich in prenylated isoflavones. This study brings an overview of dominant compounds present in selected Ficus species and points out huge differences in their phytochemical profiles.

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Publication Details

Journal
Chemistry & Biodiversity
Published
2025-04-09
DOI
https://doi.org/10.1002/cbdv.202403260
Citations
3
Primary Topic
Phytochemistry and Biological Activities
Type
article
Field-Weighted Citation Impact
5.25
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article

HPLC‐DAD and HPLC‐ELSD Profiling of Various Parts of Selected Ficus Species

Karel Šmejkal, Milan Malaník, Terézia Jedináková, Tereza Stiskálková et al.
3 citations
Chemistry & Biodiversity
Phytochemistry and Biological Activities
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article

HPLC‐DAD and HPLC‐ELSD Profiling of Various Parts of Selected Ficus Species

Karel Šmejkal, Milan Malaník, Terézia Jedináková, Tereza Stiskálková, Denisa Witteková, Anežka Chlebková
article en
3 citations

Abstract

Due to the scarcity of chemical data related to some Ficus species, forty-three ethanolic extracts were obtained from various parts of twelve Ficus species encompassing understudied ones. Thus, these were analyzed by high-performance liquid chromatography-diode array detection (HPLC-DAD) and HPLC-evaporative light scattering detection (HPLC-ELSD) to explore their phytochemical profiles. Overall, most of the extracts contain predominantly compounds lacking chromophore visible only in HPLC-ELSD chromatograms. However, HPLC-DAD analyses revealed furanocoumarins psoralen and bergapten to be dominant in extracts of all parts of F. carica and F. pumila, together with the extract of the leaves of F. cyathistipula. Some extracts (e.g., those from F. microcarpa and F. lyrata) displayed only peaks corresponding to chlorogenic acid and its derivatives. Remarkably, the extract of the roots of F. cyathistipula is rich in prenylated isoflavones. This study brings an overview of dominant compounds present in selected Ficus species and points out huge differences in their phytochemical profiles.

Chemistry & BiodiversityVol. 22(9)
Charles University (CZ), Masaryk University (CZ), University Hospital Hradec Králové (CZ)
Life in Land
Openalex Percentile: Top 6%
Phytochemistry and Biological Activities
5.25
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