Long COVID in pediatric age: an observational, prospective, longitudinal, multicenter study in Italy
The study highlights that LC in children presents similarly to adults, though less frequently. The occurrence of LC was lower compared to adult populations, likely due to the generally milder course of COVID-19 in children. The findings underscore the need for targeted follow-up and support for affected children, especially considering the long-term persistence of symptoms. Further research is necessary to explore the impact of COVID-19 vaccines on pediatric LC and the effects of different SARS-CoV-2 variants. These insights are crucial for developing strategies to manage and mitigate long-term impacts in children recovering from COVID-19.
Authors
- Samantha Bosis (ORCID: https://orcid.org/0000-0003-2288-2633)
- Susanna Esposito (ORCID: https://orcid.org/0000-0003-4103-2837)
- Caterina Caminiti (ORCID: https://orcid.org/0000-0002-3196-2435)
- Matteo Puntoni (ORCID: https://orcid.org/0000-0002-7908-0626)
- Elio Castagnola (ORCID: https://orcid.org/0000-0002-5336-8429)
- Claudia Colomba (ORCID: https://orcid.org/0000-0003-3245-9396)
- Michela Deolmi
- Fabio Cardinale (ORCID: https://orcid.org/0000-0002-6774-6152)
- Stefania Zampogna (ORCID: https://orcid.org/0000-0002-8469-7129)
- Marco Poeta (ORCID: https://orcid.org/0000-0002-7515-1394)
- Carlo Giaquinto (ORCID: https://orcid.org/0000-0001-9365-0413)
- Agnese Suppiej (ORCID: https://orcid.org/0000-0001-5130-1450)
- Francesco Nunziata (ORCID: https://orcid.org/0000-0002-7351-4104)
- Greta Ramundo
- Valentina Fainardi (ORCID: https://orcid.org/0000-0003-4601-7484)
- Anna Condemi
- Giuseppe Maglietta (ORCID: https://orcid.org/0000-0003-4497-1872)
- Alfredo Guarino (ORCID: https://orcid.org/0000-0003-0199-0336)
- Roberto Grandinetti (ORCID: https://orcid.org/0000-0002-1341-761X)
- Fabio Midulla (ORCID: https://orcid.org/0000-0001-7476-5266)
- Giacomo Biasucci (ORCID: https://orcid.org/0000-0002-7441-9248)
- Paola Giordano (ORCID: https://orcid.org/0000-0002-7762-3500)
- Giuseppe Raiola
Institutions
- University of Parma (IT)
- University of Padua (IT)
- University of Ferrara (IT)
- Istituto Giannina Gaslini (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Istituto S.Anna Crotone (IT)
- Federico II University Hospital (IT)
- Guglielmo da Saliceto Hospital (IT)
- Ospedale Pediatrico Giovanni XXIII (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Azienda Ospedaliera Pugliese Ciaccio (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Bari Aldo Moro (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1466201
- Citations
- 5
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 6.95
Funders
- European Commission