The #HOPE4LIVER Single-arm Pivotal Trial for Histotripsy of Primary and Metastatic Liver Tumors
Histotripsy results in local control of liver tumors at 1 year, which is consistent with current locoregional therapies. The safety profile is favorable, and survival at 1 year is comparable with other therapies for similar disease stages.
Authors
- Mathis Planert (ORCID: https://orcid.org/0000-0003-1419-1891)
- Timothy J. Ziemlewicz (ORCID: https://orcid.org/0000-0002-7033-1062)
- Sarah B. White (ORCID: https://orcid.org/0000-0002-6870-6400)
- Philipp Wiggermann (ORCID: https://orcid.org/0000-0003-4424-7489)
- Neehar D. Parikh (ORCID: https://orcid.org/0000-0002-5874-9933)
- Maciej Pech (ORCID: https://orcid.org/0000-0002-7140-6775)
- Tze Min Wah (ORCID: https://orcid.org/0000-0001-5670-5454)
- Peter Littler (ORCID: https://orcid.org/0009-0006-3529-4303)
- Jeff Critchfield (ORCID: https://orcid.org/0000-0002-7694-2550)
- Xavier Serres (ORCID: https://orcid.org/0000-0001-8642-467X)
- Maximilian Thormann (ORCID: https://orcid.org/0000-0003-3822-8871)
- Guido Torzilli (ORCID: https://orcid.org/0000-0001-5798-5021)
- Mishal Mendiratta‐Lala (ORCID: https://orcid.org/0000-0003-4055-916X)
- Zachary Collins (ORCID: https://orcid.org/0000-0003-2641-7990)
- Osman Ahmed (ORCID: https://orcid.org/0000-0003-2440-2437)
- Govindarajan Narayanan (ORCID: https://orcid.org/0000-0002-8659-0894)
- Clifford S. Cho (ORCID: https://orcid.org/0000-0002-9577-7626)
- Luigi Solbiati (ORCID: https://orcid.org/0000-0002-3109-1449)
- Meghan Lubner
- Clifford Davis
Institutions
- Baptist Hospital of Miami (US)
- University of Leeds (GB)
- Wyoming State Department of Health (US)
- Van Andel Institute (US)
- Humanitas University (IT)
- University of Wisconsin–Madison (US)
- Wayne State University (US)
- Medical College of Wisconsin (US)
- University of Michigan (US)
- Leeds Teaching Hospitals NHS Trust (GB)
- Metro Health Hospital (US)
- West Health (US)
- Freeman Hospital (GB)
- Tampa General Hospital (US)
- University of Chicago (US)
- The Barbara Ann Karmanos Cancer Institute (US)
- Klinikum Magdeburg (DE)
- Michigan Medicine (US)
- Klinikum Braunschweig (DE)
- Vall d'Hebron Hospital Universitari (ES)
- University of Kansas Medical Center (US)
- University of Wisconsin Health (US)
- University Hospital Magdeburg (DE)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Annals of Surgery
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1097/sla.0000000000006720
- Citations
- 20
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 26.44