Laparoscopic treatment of a rare primary peritoneal serous borderline tumor: Case report and narrative review of the literature

Primary peritoneal serous borderline tumors (PPSBT) are epithelial proliferations with low malignant potential, but they are rare entities. Due to their rarity, PPSBTs are often misdiagnosed as undiagnosed diffuse primary ovarian carcinomas. This leads to unnecessary and more aggressive treatments. Tough, accurate recognition of PPSBT is crucial in clinical practice. This narrative review examines the current literature to provide practical guidance on the diagnosis and management of PPSBT. A key methodological choice in this review is the inclusion of a clinical case, which serves to contextualize the literature evidence in a real-world scenario. The case involves a 51-year-old asymptomatic woman who underwent laparoscopic excision and staging of a 99x51 mm mass, later confirmed as a PPSBT staged IA sec FIGO. The patient's recovery was uneventful, and she remains disease-free after two years. This case, one of the few laparoscopically treated examples in the literature, underscores the value of minimally invasive surgery for both excision and staging and reinforces the importance of accurate diagnosis in improving clinical outcomes for PPSBT.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2025-04-09
DOI
https://doi.org/10.1016/j.gore.2025.101742
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Laparoscopic treatment of a rare primary peritoneal serous borderline tumor: Case report and narrative review of the literature

Roberta Granese, Luigi Alfano, Antonio Giordano, Canio Martinelli et al.
Gynecologic Oncology Reports
Intraperitoneal and Appendiceal Malignancies
article

Laparoscopic treatment of a rare primary peritoneal serous borderline tumor: Case report and narrative review of the literature

Roberta Granese, Luigi Alfano, Antonio Giordano, Canio Martinelli, Alfredo Ercoli, Patrizia Maiorano, Salvatore Cortellino, Vito Iannone, Maddalena Borriello, Alessia Maria Chiara Scaparra Caronna
article en

Abstract

Primary peritoneal serous borderline tumors (PPSBT) are epithelial proliferations with low malignant potential, but they are rare entities. Due to their rarity, PPSBTs are often misdiagnosed as undiagnosed diffuse primary ovarian carcinomas. This leads to unnecessary and more aggressive treatments. Tough, accurate recognition of PPSBT is crucial in clinical practice. This narrative review examines the current literature to provide practical guidance on the diagnosis and management of PPSBT. A key methodological choice in this review is the inclusion of a clinical case, which serves to contextualize the literature evidence in a real-world scenario. The case involves a 51-year-old asymptomatic woman who underwent laparoscopic excision and staging of a 99x51 mm mass, later confirmed as a PPSBT staged IA sec FIGO. The patient's recovery was uneventful, and she remains disease-free after two years. This case, one of the few laparoscopically treated examples in the literature, underscores the value of minimally invasive surgery for both excision and staging and reinforces the importance of accurate diagnosis in improving clinical outcomes for PPSBT.

Gynecologic Oncology ReportsVol. 59
University of Siena (IT), University of Messina (IT), Ospedale Sant Antonio (IT), Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT), Temple University (US)
Good health and well-being
Openalex Percentile: Top 88%
Intraperitoneal and Appendiceal Malignancies
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