HISTOPATHOLOGYC AND DERMOSCOPIC FINDINGS OF SUBACUTE CUTANEOUS LUPUSERYTHEMATOSUS
The relevance, pathogenesis, classification, and clinical characteristics of a rare disease-subacute cutaneous lupus erythematosus-are presented. A clinical case in a 60-year-old woman without signs of organ pathology is also described. A dermatoscopic examination was performed. In the affected areas on the facial skin, twisted, short linear, occasionally branching, unfocused vessels, predominantly bright red in color, forming incomplete polygonal structures, were identified. In the affected areas on the skin of the extremities, irregularly arranged dotted-granular and twisted short linear vessels of dull red color were visualized, along with structureless zones of varying degrees of discoloration, exhibiting whitish-orange shades. Pathomorphologically, the process is characterized by mild focal hyperkeratosis, vacuolar degeneration of the basal layer of the epidermis, a mildly expressed perivascular lymphohistiocytic inflammatory infiltrate, as well as a moderately expressed periadnexal (perieccrine) lymphohistiocytic inflammatory infiltrate.Based on the medical history, clinical presentation, and the results of dermoscopic and histological examinations, the diagnosis of psoriasiform subacute cutaneous lupus erythematosus was established.
Authors
- Hovhannes Hovhannisyan
- Ա. Պ. Թոփչյան
- Khachik Khachikyan (ORCID: https://orcid.org/0000-0002-8625-2764)
- Armine Hakobyan
- Anj Giragos
Institutions
- Yerevan State Medical University (AM)
Publication Details
- Journal
- BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY
- Published
- 2025-03-20
- DOI
- https://doi.org/10.58240/1829006x-2025.3-313
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00