HISTOPATHOLOGYC AND DERMOSCOPIC FINDINGS OF SUBACUTE CUTANEOUS LUPUSERYTHEMATOSUS

The relevance, pathogenesis, classification, and clinical characteristics of a rare disease-subacute cutaneous lupus erythematosus-are presented. A clinical case in a 60-year-old woman without signs of organ pathology is also described. A dermatoscopic examination was performed. In the affected areas on the facial skin, twisted, short linear, occasionally branching, unfocused vessels, predominantly bright red in color, forming incomplete polygonal structures, were identified. In the affected areas on the skin of the extremities, irregularly arranged dotted-granular and twisted short linear vessels of dull red color were visualized, along with structureless zones of varying degrees of discoloration, exhibiting whitish-orange shades. Pathomorphologically, the process is characterized by mild focal hyperkeratosis, vacuolar degeneration of the basal layer of the epidermis, a mildly expressed perivascular lymphohistiocytic inflammatory infiltrate, as well as a moderately expressed periadnexal (perieccrine) lymphohistiocytic inflammatory infiltrate.Based on the medical history, clinical presentation, and the results of dermoscopic and histological examinations, the diagnosis of psoriasiform subacute cutaneous lupus erythematosus was established.

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Journal
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY
Published
2025-03-20
DOI
https://doi.org/10.58240/1829006x-2025.3-313
Primary Topic
Systemic Lupus Erythematosus Research
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article
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article

HISTOPATHOLOGYC AND DERMOSCOPIC FINDINGS OF SUBACUTE CUTANEOUS LUPUSERYTHEMATOSUS

Hovhannes Hovhannisyan, Ա. Պ. Թոփչյան, Khachik Khachikyan, Armine Hakobyan et al.
BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY
Systemic Lupus Erythematosus Research
article

HISTOPATHOLOGYC AND DERMOSCOPIC FINDINGS OF SUBACUTE CUTANEOUS LUPUSERYTHEMATOSUS

Hovhannes Hovhannisyan, Ա. Պ. Թոփչյան, Khachik Khachikyan, Armine Hakobyan, Anj Giragos
article en

Abstract

The relevance, pathogenesis, classification, and clinical characteristics of a rare disease-subacute cutaneous lupus erythematosus-are presented. A clinical case in a 60-year-old woman without signs of organ pathology is also described. A dermatoscopic examination was performed. In the affected areas on the facial skin, twisted, short linear, occasionally branching, unfocused vessels, predominantly bright red in color, forming incomplete polygonal structures, were identified. In the affected areas on the skin of the extremities, irregularly arranged dotted-granular and twisted short linear vessels of dull red color were visualized, along with structureless zones of varying degrees of discoloration, exhibiting whitish-orange shades. Pathomorphologically, the process is characterized by mild focal hyperkeratosis, vacuolar degeneration of the basal layer of the epidermis, a mildly expressed perivascular lymphohistiocytic inflammatory infiltrate, as well as a moderately expressed periadnexal (perieccrine) lymphohistiocytic inflammatory infiltrate.Based on the medical history, clinical presentation, and the results of dermoscopic and histological examinations, the diagnosis of psoriasiform subacute cutaneous lupus erythematosus was established.

BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY
Yerevan State Medical University (AM)
Openalex Percentile: Top 89%
Systemic Lupus Erythematosus Research
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