Ferroptosis-related protein biomarkers for diagnosis, differential diagnosis, and short-term mortality in patients with sepsis in the intensive care unit
ACSL4 and GPX4 have strong diagnostic and differential diagnostic value in sepsis, including the ability to predict 28-day mortality in sepsis patients, and may become new potential serum markers for the diagnostic and differential diagnostic of sepsis.
Authors
- Wenchao Xie
- Wenzhong Xiao (ORCID: https://orcid.org/0000-0003-4944-6380)
- Zhangrui Zeng (ORCID: https://orcid.org/0000-0001-9099-8342)
- Ke Li (ORCID: https://orcid.org/0000-0002-3007-978X)
- Jinbo Liu (ORCID: https://orcid.org/0000-0001-9042-2829)
- Jie Deng (ORCID: https://orcid.org/0000-0002-2181-2273)
- Gang Wang (ORCID: https://orcid.org/0000-0002-9369-0738)
- Zhongbao Luo
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- First Affiliated Hospital of Sichuan Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.3389/fimmu.2025.1528986
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 6.07
Funders
- Southwest Medical University