Crocin-I mitigates diquat-induced pulmonary fibrosis via activation of the SIRT3/FOXO3a pathway

These findings suggest that crocin-I activates the SIRT3/FOXO3a pathway and alleviates DQ-induced pulmonary fibrosis, highlighting its potential as a therapeutic agent for lung injury and paving the way for further research into its clinical applications.

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Publication Details

Journal
Biomedicine & Pharmacotherapy
Published
2025-04-08
DOI
https://doi.org/10.1016/j.biopha.2025.118043
Citations
2
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
3.04
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article

Crocin-I mitigates diquat-induced pulmonary fibrosis via activation of the SIRT3/FOXO3a pathway

Weijun Chen, Xiuli Li, Yong Cao, Yong Ke et al.
2 citations
Biomedicine & Pharmacotherapy
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
3.04
article

Crocin-I mitigates diquat-induced pulmonary fibrosis via activation of the SIRT3/FOXO3a pathway

Weijun Chen, Xiuli Li, Yong Cao, Yong Ke, Shuangyun Xi
article en
2 citations

Abstract

These findings suggest that crocin-I activates the SIRT3/FOXO3a pathway and alleviates DQ-induced pulmonary fibrosis, highlighting its potential as a therapeutic agent for lung injury and paving the way for further research into its clinical applications.

Biomedicine & PharmacotherapyVol. 186
Zunyi Medical University (CN)
Openalex Percentile: Top 10%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
3.04
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