Nickel-catalyzed enantioselective reductive iminodisulfuration of alkene-tethered oxime esters with dithiosulfonate
A novel nickel-catalyzed enantioselective reductive iminodisulfuration of alkene-tethered oxime esters with dithiosulfonate is presented in this study. This reaction exhibits exceptional regio- and enantioselectivity, showing broad substrate compatibility. Gram-scale synthesis of chiral pyrroline disulfide and versatile subsequent conversions highlight the synthetic utility of this scaffold.
Authors
- Min Nie (ORCID: https://orcid.org/0000-0001-7179-0044)
- Qianwen Gao (ORCID: https://orcid.org/0009-0007-7341-1424)
- Zhizheng Chen
- Wen‐Yan Tong
- Jie Zhou (ORCID: https://orcid.org/0000-0002-0769-2543)
- Hang Yan (ORCID: https://orcid.org/0000-0003-3912-0168)
- Shuanglin Qu (ORCID: https://orcid.org/0000-0002-8122-9848)
- Haonan Wei (ORCID: https://orcid.org/0009-0006-7772-7840)
- Wenhao Li (ORCID: https://orcid.org/0000-0001-9869-145X)
- Xi Wang (ORCID: https://orcid.org/0000-0003-1064-9973)
Institutions
- Hunan University (CN)
- Ministry of Education (SA)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc01654a
- Primary Topic
- Chemical Synthesis and Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00