Intracranial neuromodulation for pediatric drug-resistant epilepsy: early institutional experience
In the early Stanford experience, DBS was used as a palliatively for generalized or mixed DRE refractory to other resective or modulatory approaches. RNS was used for multifocal DRE with a clear seizure focus on stereo-EEG and no prior surgical interventions. Both modalities reduced seizure burden across all patients. RNS offers the additional benefit of providing data to guide future surgical planning.
Authors
- Gerald A. Grant (ORCID: https://orcid.org/0000-0002-2651-4603)
- H. Westley Phillips (ORCID: https://orcid.org/0000-0003-0512-4590)
- Ann Hyslop (ORCID: https://orcid.org/0000-0002-2971-7131)
- Jonathon J. Parker (ORCID: https://orcid.org/0000-0002-0531-8400)
- Vivek Buch (ORCID: https://orcid.org/0000-0003-1151-6128)
- Kevin K. Kumar (ORCID: https://orcid.org/0000-0002-0704-1492)
- Juliet K. Knowles (ORCID: https://orcid.org/0000-0002-9214-2991)
- Casey H. Halpern (ORCID: https://orcid.org/0000-0003-3907-216X)
- Julie Uchitel (ORCID: https://orcid.org/0000-0003-4568-5421)
- Austin Lui (ORCID: https://orcid.org/0000-0003-1347-8815)
Institutions
- Lucile Packard Children's Hospital (US)
- Duke University (US)
- Touro University California (US)
- Hospital of the University of Pennsylvania (US)
- The University of Texas at Austin (US)
- Stanford University (US)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2025-04-08
- DOI
- https://doi.org/10.3389/fsurg.2025.1569360
- Citations
- 3
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.17