Time‐Resolved Imaging of Contrast Kinetics for Canine Hindlimb Angiography: A Comparison With CT Angiography and Noncontrast Magnetic Resonance Angiography

This study aimed to evaluate the feasibility of time-resolved imaging of contrast kinetics (TRICKS) for visualizing hindlimb vasculature in normal dogs and to compare it with CT angiography (CTA) and noncontrast magnetic resonance angiography (MRA). In a method-comparison prospective study, CTA and MRA, including three-dimensional time-of-flight (TOF), phase-contrast, and TRICKS sequences, were performed on the bilateral hindlimbs of six healthy beagles. Vascular distinction, delineation, connectivity, visualization, and image quality were qualitatively assessed. The relative signal intensity and acquisition time were measured. TRICKS provided better vascular distinction, delineation, and connectivity in both the proximal and distal regions compared with phase-contrast and TOF, and its image quality was comparable to that of CTA. TRICKS also demonstrated excellent differentiation between arteries and veins, which was attributable to the use of contrast agents and high temporal resolution, allowing for detailed visualization of both large and small vessels. Although artifacts were occasionally observed in TRICKS, they did not affect the overall image quality. Although the phase-contrast sequence performed well in visualizing larger vessels, it showed significant limitations in smaller branches and vessel connectivity. TOF suffers from artifacts and long acquisition times, rendering it less effective for the peripheral vasculature. These findings suggest that TRICKS is a feasible and valuable tool for detailed hindlimb vasculature imaging, offering improved visualization and rapid acquisition compared with noncontrast MRA techniques.

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Publication Details

Journal
Veterinary Radiology & Ultrasound
Published
2025-04-07
DOI
https://doi.org/10.1111/vru.70025
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Time‐Resolved Imaging of Contrast Kinetics for Canine Hindlimb Angiography: A Comparison With CT Angiography and Noncontrast Magnetic Resonance Angiography

Nahyun Kwon, Sam-Sun Lee, Junghee Yoon, Sujung Wang et al.
Veterinary Radiology & Ultrasound
Advanced MRI Techniques and Applications
article

Time‐Resolved Imaging of Contrast Kinetics for Canine Hindlimb Angiography: A Comparison With CT Angiography and Noncontrast Magnetic Resonance Angiography

Nahyun Kwon, Sam-Sun Lee, Junghee Yoon, Sujung Wang, Jihye Choi, Sunghwa Hong, Hyeonjae Woo, Mire Namgoong
article en

Abstract

This study aimed to evaluate the feasibility of time-resolved imaging of contrast kinetics (TRICKS) for visualizing hindlimb vasculature in normal dogs and to compare it with CT angiography (CTA) and noncontrast magnetic resonance angiography (MRA). In a method-comparison prospective study, CTA and MRA, including three-dimensional time-of-flight (TOF), phase-contrast, and TRICKS sequences, were performed on the bilateral hindlimbs of six healthy beagles. Vascular distinction, delineation, connectivity, visualization, and image quality were qualitatively assessed. The relative signal intensity and acquisition time were measured. TRICKS provided better vascular distinction, delineation, and connectivity in both the proximal and distal regions compared with phase-contrast and TOF, and its image quality was comparable to that of CTA. TRICKS also demonstrated excellent differentiation between arteries and veins, which was attributable to the use of contrast agents and high temporal resolution, allowing for detailed visualization of both large and small vessels. Although artifacts were occasionally observed in TRICKS, they did not affect the overall image quality. Although the phase-contrast sequence performed well in visualizing larger vessels, it showed significant limitations in smaller branches and vessel connectivity. TOF suffers from artifacts and long acquisition times, rendering it less effective for the peripheral vasculature. These findings suggest that TRICKS is a feasible and valuable tool for detailed hindlimb vasculature imaging, offering improved visualization and rapid acquisition compared with noncontrast MRA techniques.

Veterinary Radiology & UltrasoundVol. 66(3)
Seoul National University (KR)
Ministry of Science, ICT and Future Planning
Openalex Percentile: Top 89%
Advanced MRI Techniques and Applications
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