The improvement in muscle function following statin withdrawal might involve the repair of the neuromuscular junction
Altogether, statin usage was associated with muscle and physical decline and an increase in CAF22 and SAMS, which were partly restored after statin withdrawal. Our findings suggest a role for NMJ plasticity in muscle restoration following statin withdrawal.
Authors
- Imran Khan (ORCID: https://orcid.org/0000-0002-2069-7410)
- Rizwan Qaisar (ORCID: https://orcid.org/0000-0001-8485-7172)
- Shaea Ayed Alkahtani (ORCID: https://orcid.org/0000-0002-1443-6249)
- Asima Karim (ORCID: https://orcid.org/0000-0002-6288-0686)
- Firdos Ahmad (ORCID: https://orcid.org/0000-0001-6530-6068)
Institutions
- King Saud University (SA)
- University of Sharjah (AE)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1002/bcp.70065
- Citations
- 3
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- University of Sharjah