Response and remission after first-line corticosteroid therapy in primary immune thrombocytopenia

Corticosteroids are effective first-line therapy for ITP, but are not remission-inducing in all patients. For those patients progressing to chronic ITP, there is a need to investigate cost-effective treatment. Some patients are at high risk of developing new hypertension and diabetes mellitus on corticosteroids, and should be monitored.

Authors

Jennifer M. Bailey (ORCID: https://orcid.org/0000-0002-4750-106X)
Estelle Verburgh (ORCID: https://orcid.org/0000-0003-4657-7318)
Karryn Brown (ORCID: https://orcid.org/0000-0002-6132-4717)
Jenique Bailly (ORCID: https://orcid.org/0000-0002-6542-6956)
D Mapimhidze

Institutions

University of Cape Town (ZA)
Groote Schuur Hospital (ZA)

Publication Details

Journal: South African Medical Journal
Published: 2025-02-28
DOI: https://doi.org/10.7196/samj.2025.v115i2.2191
Primary Topic: Platelet Disorders and Treatments
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Institutes of Health
Fogarty International Center

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article

Response and remission after first-line corticosteroid therapy in primary immune thrombocytopenia

Jennifer M. Bailey, Estelle Verburgh, Karryn Brown, Jenique Bailly et al.

Feb 28, 2025

South African Medical Journal

Platelet Disorders and Treatments

article

Response and remission after first-line corticosteroid therapy in primary immune thrombocytopenia

Jennifer M. Bailey, Estelle Verburgh, Karryn Brown, Jenique Bailly, D Mapimhidze

February 28, 2025article en

Abstract

Corticosteroids are effective first-line therapy for ITP, but are not remission-inducing in all patients. For those patients progressing to chronic ITP, there is a need to investigate cost-effective treatment. Some patients are at high risk of developing new hypertension and diabetes mellitus on corticosteroids, and should be monitored.

South African Medical JournalVol. 115(2)

University of Cape Town (ZA), Groote Schuur Hospital (ZA)

National Institutes of Health, Fogarty International Center

Openalex Percentile: Top 91%

Platelet Disorders and Treatments

DOI Open Access PDF OpenAlex

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