Silencing circRNA-ZFAND6 induces trophoblast apoptosis by activating the mitochondrial pathway through the miR-575/SOD2 axis in unexplained recurrent spontaneous abortion
CircRNA-ZFAND6, which is low expressed in URSA and regulates the apoptosis of trophoblast cells, may affect the expression of SOD2 and thus affect mitochondrial apoptosis by regulating miR-575. This is closely related to the occurrence of URSA.
Authors
- Zhijing Miao
- Shan Li (ORCID: https://orcid.org/0000-0001-7286-8456)
- Wenting Wang (ORCID: https://orcid.org/0000-0002-8344-0102)
- Juan Lv
- Linxiang Huang (ORCID: https://orcid.org/0000-0001-5140-6148)
- Shuping Jin
- Qing Cheng (ORCID: https://orcid.org/0000-0003-3082-998X)
Institutions
- Nanjing Maternity and Child Health Care Hospital (CN)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1186/s12905-025-03682-7
- Citations
- 3
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Nanjing Medical Science and Technique Development Foundation