Ultrasound-guided microfragmented adipose graft injection to regenerate a large partial-thickness Achilles tendon rupture: a case report

Partial-thickness Achilles rupture appears to be a neglected diagnosis in the medical community and lacks an adequate standard treatment regimen. Currently, conservative treatment options include a combination of rest, physical therapy, bracing, and anti-inflammatory medications. When these conservative measures fail, or in cases where the partial Achilles rupture is large, surgical repair is usually required to regain the function of the gastroc-soleus complex. However, this case represents the second documented circumstance where regenerative medicine was able to fully repair a large partial-thickness Achilles rupture. We present a case report of a 69-year-old man diagnosed with a left large partial-thickness Achilles rupture following an acute sport injury. The patient expressed a desire to return to moderate athletic activity for his age group and was treated with autologous micro-fragmented adipose transfer. He was re-evaluated at 5 weeks and again at 10 weeks post-treatment and demonstrated musculoskeletal sonographic evidence of complete resolution and remodeling of his partial thickness Achilles rupture. This case presents a promising option for patients with partial thickness Achilles ruptures who would like to refrain from or are unable to have surgery. Further research and possible randomized controlled trials are needed to further assess the full efficacy of micro-fragmented adipose transfer in the treatment of partial thickness Achilles ruptures.

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Publication Details

Journal
Regenerative medicine reports .
Published
2025-04-08
DOI
https://doi.org/10.4103/regenmed.regenmed-d-25-00008
Citations
1
Primary Topic
Tendon Structure and Treatment
Type
article
Field-Weighted Citation Impact
1.72
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article

Ultrasound-guided microfragmented adipose graft injection to regenerate a large partial-thickness Achilles tendon rupture: a case report

C Umesh, Kyle J. Dineen, Roosevelt Desronvilles, Imran Siddiqui et al.
1 citations
Regenerative medicine reports .
Tendon Structure and Treatment
1.72
article

Ultrasound-guided microfragmented adipose graft injection to regenerate a large partial-thickness Achilles tendon rupture: a case report

C Umesh, Kyle J. Dineen, Roosevelt Desronvilles, Imran Siddiqui, Sanjay Mahadevan
article en
1 citations

Abstract

Partial-thickness Achilles rupture appears to be a neglected diagnosis in the medical community and lacks an adequate standard treatment regimen. Currently, conservative treatment options include a combination of rest, physical therapy, bracing, and anti-inflammatory medications. When these conservative measures fail, or in cases where the partial Achilles rupture is large, surgical repair is usually required to regain the function of the gastroc-soleus complex. However, this case represents the second documented circumstance where regenerative medicine was able to fully repair a large partial-thickness Achilles rupture. We present a case report of a 69-year-old man diagnosed with a left large partial-thickness Achilles rupture following an acute sport injury. The patient expressed a desire to return to moderate athletic activity for his age group and was treated with autologous micro-fragmented adipose transfer. He was re-evaluated at 5 weeks and again at 10 weeks post-treatment and demonstrated musculoskeletal sonographic evidence of complete resolution and remodeling of his partial thickness Achilles rupture. This case presents a promising option for patients with partial thickness Achilles ruptures who would like to refrain from or are unable to have surgery. Further research and possible randomized controlled trials are needed to further assess the full efficacy of micro-fragmented adipose transfer in the treatment of partial thickness Achilles ruptures.

Regenerative medicine reports .Vol. 2(2)
Center for Neuroscience and Regenerative Medicine (US)
Openalex Percentile: Top 20%
Tendon Structure and Treatment
1.72
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Ultrasound-guided microfragmented adipose graft injection to regenerate a large partial-thickness Achilles tendon rupture: a case report — C Umesh, Kyle J. Dineen, et al. · Regenerative medicine reports . (2025) | TGRS Research Map | TGRS